Innovative Medicine (Record no. 1355)

000 -LEADER
fixed length control field 05750nam a22005775i 4500
001 - CONTROL NUMBER
control field 978-4-431-55651-0
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20210511121824.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 151013s2015 ja | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9784431556510
-- 978-4-431-55651-0
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-4-431-55651-0
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH506
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBGR
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI049000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBGR
Source thema
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSD
Source thema
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 611.01816
Edition number 23
245 10 - TITLE STATEMENT
Title Innovative Medicine
Medium [electronic resource] :
Remainder of title Basic Research and Development /
Statement of responsibility, etc. edited by Kazuwa Nakao, Nagahiro Minato, Shinji Uemoto.
250 ## - EDITION STATEMENT
Edition statement 1st ed. 2015.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Tokyo :
Name of producer, publisher, distributor, manufacturer Springer Japan :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2015.
300 ## - PHYSICAL DESCRIPTION
Extent IX, 339 p.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Part I Basic Research for Innovative Medicine -- 1. Diverting Glycolysis to Combat Oxidative Stress -- 2. Metabolic Regulation by Nuclear Receptors -- 3. Fighting Fire with Fire in Cancer -- 4. Linear Polyubiquitination: a Crucial Regulator of NF-kB Activation -- 5. VCP, a major ATPase in the cells, as a novel drug target for currently incurable disorders -- 6. Roles of E-cadherin in hepatocarcinogenesis -- 7. The Hippo Signaling Pathway: A Candidate New Drug Target for Malignant Tumors -- 8. Inhibitory immunoreceptors on mast cells in allergy and inflammation -- 9. Doxycycline-inducible Autoimmune Blistering Skin Disease Model -- 10. T-cell Senescence and Autoimmunity -- Part II Translational Research for Innovative Medicine -- 11. IL-6: A new era for the treatment of autoimmune inflammatory diseases -- 12. Pathogenesis of Non-alcoholic Steatohepatitis and Its Potential Therapeutic Strategies -- 13. Multifaceted translational approach of major mental illness -- 14. Translational research of leptin in lipodystrophy and its related diseases -- 15. Translational research of the activation of the C-type natriuretic peptide (CNP)-guanylyl cyclase-B pathway for skeletal dysplasia -- 16. Clarity and Challenges in Tissue Fibrosis -- 17. TRP Channels: Their Function and Potentiality as Drug Targets -- 18. Autophagic Cell Death and Cancer Chemotherapeutics -- 19. Adrenomedullin as a Potential Therapeutic Agent for Refractory Ulcerative Colitis -- 20. RNA activation -- Part III New Technology for Innovative Medicine -- 21. Cardiac Reprogramming for Heart Repair -- 22. Development of a new in vivo optical probe for biological diagnosis and therapy -- 23. Introduction of mesenchymal stem cells for liver surgery (hepatectomy and transplantation) -- 24. Synaptic and axonal plasticity induction in the human cerebral cortex -- 25. TIM-3 is a novel therapeutic target for eradicating acute myelogenous leukemia stem cells -- 26. TGF-beta LAP degradation products, a novel biomarker and promising therapeutic target for liver fibrogenesis -- 27. Cell-based regenerative therapy for liver disease.
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
520 ## - SUMMARY, ETC.
Summary, etc. This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular biology.
9 (RLIN) 727
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Immunology.
9 (RLIN) 4937
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell biology.
9 (RLIN) 6638
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Medicine.
Authority record control number or standard number https://scigraph.springernature.com/ontologies/product-market-codes/B1700X
9 (RLIN) 732
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Immunology.
Authority record control number or standard number https://scigraph.springernature.com/ontologies/product-market-codes/B14000
9 (RLIN) 4937
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Biology.
Authority record control number or standard number https://scigraph.springernature.com/ontologies/product-market-codes/L16008
9 (RLIN) 6639
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Nakao, Kazuwa.
Relator term editor.
Relationship edt
-- http://id.loc.gov/vocabulary/relators/edt
9 (RLIN) 6640
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Minato, Nagahiro.
Relator term editor.
Relationship edt
-- http://id.loc.gov/vocabulary/relators/edt
9 (RLIN) 6641
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Uemoto, Shinji.
Relator term editor.
Relationship edt
-- http://id.loc.gov/vocabulary/relators/edt
9 (RLIN) 6642
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
9 (RLIN) 141
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9784431556527
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9784431556503
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9784431562467
773 ## - HOST ITEM ENTRY
Title Springer Nature Open Access eBook
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1007/978-4-431-55651-0">https://doi.org/10.1007/978-4-431-55651-0</a>
912 ## -
-- ZDB-2-SBL
912 ## -
-- ZDB-2-SXB
912 ## -
-- ZDB-2-SOB
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type e-Books
-- Administrator Library

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