Evaluating Evidence of Mechanisms in Medicine (Record no. 1106)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05798nam a22006375i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-319-94610-8 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20210511121040.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180713s2018 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783319946108 |
| -- | 978-3-319-94610-8 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-319-94610-8 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R723-723.7 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | HP |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED050000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | QD |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610.1 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Parkkinen, Veli-Pekka. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5442 |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluating Evidence of Mechanisms in Medicine |
| Medium | [electronic resource] : |
| Remainder of title | Principles and Procedures / |
| Statement of responsibility, etc. | by Veli-Pekka Parkkinen, Christian Wallmann, Michael Wilde, Brendan Clarke, Phyllis Illari, Michael P Kelly, Charles Norell, Federica Russo, Beth Shaw, Jon Williamson. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2018. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Cham : |
| Name of producer, publisher, distributor, manufacturer | Springer International Publishing : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2018. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XVIII, 125 p. 14 illus. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | SpringerBriefs in Philosophy, |
| International Standard Serial Number | 2211-4548 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1 Introduction -- 1.1 What is a mechanism? -- 1.2 Where does evidence of a mechanism come from? -- 1.3 Why consider evidence of mechanisms? -- 1.3.1 Evaluating efficacy -- 1.3.2 Evaluating external validity -- 1.3.3 Other questions -- 1.3.4 Importance of considering evidence of mechanisms -- 2 How to consider evidence of mechanisms: a summary -- 2.1 Questions to address -- 2.2 Quality level of evidence and status of claim -- 2.3 Identifying evidence of mechanisms in the literature -- 2.4 Evaluating evidence of mechanisms -- 2.5 Using evidence of mechanisms to evaluate causal claims -- 2.6 Overall approach -- 3 Identifying evidence of mechanisms in the literature -- 3.1 Hypothesize a mechanism -- 3.2 Search the literature -- 3.3 Identify the evidence most relevant to the mechanism hypothesis -- 3.4 Presenting the evidence of mechanisms -- 4 Evaluating evidence of mechanisms -- 4.1 Considerations for evaluating evidence of mechanism -- 4.2 Presenting quality of evidence of mechanisms -- 5 Using evidence of mechanisms to evaluate efficacy and external validity -- 5.1 Efficacy -- 5.2 External validity -- 6 Glossary -- 7 References -- 8 Acknowledgements -- 9 Appendix A. A critical appraisal tool for evidence of mechanisms -- 10 Appendix B. GRADE tables with mechanism assessment -- 11 Appendix C: Databases for evidence of mechanisms -- 12 Appendix D: Assessing exposures -- 12.1 Example: carcinogenicity of benzo[a]pyrene -- 12.2 Comparison to IARC -- 12.3 Molecular epidemiology -- 12.4 Comparison to SYRINA. |
| 506 0# - RESTRICTIONS ON ACCESS NOTE | |
| Terms governing access | Open Access |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine—Philosophy. |
| 9 (RLIN) | 4544 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Epistemology. |
| 9 (RLIN) | 975 |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Philosophy of Medicine. |
| Authority record control number or standard number | https://scigraph.springernature.com/ontologies/product-market-codes/E34030 |
| 9 (RLIN) | 4545 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Epistemology. |
| Authority record control number or standard number | https://scigraph.springernature.com/ontologies/product-market-codes/E13000 |
| 9 (RLIN) | 975 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wallmann, Christian. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5443 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wilde, Michael. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5444 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Clarke, Brendan. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5445 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Illari, Phyllis. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5446 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kelly, Michael P. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5447 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Norell, Charles. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5448 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Russo, Federica. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5449 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shaw, Beth. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5450 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Williamson, Jon. |
| Relator term | author. |
| Relationship | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 9 (RLIN) | 5451 |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 9 (RLIN) | 141 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9783319946092 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9783319946115 |
| 773 ## - HOST ITEM ENTRY | |
| Title | Springer Nature Open Access eBook |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | SpringerBriefs in Philosophy, |
| International Standard Serial Number | 2211-4548 |
| 9 (RLIN) | 5441 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-3-319-94610-8">https://doi.org/10.1007/978-3-319-94610-8</a> |
| 912 ## - | |
| -- | ZDB-2-REP |
| 912 ## - | |
| -- | ZDB-2-SXPR |
| 912 ## - | |
| -- | ZDB-2-SOB |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | e-Books |
| -- | Administrator Library |
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